MBTPS1 Products

Antibodies
MBTPS1 Antibody
MBTPS1 Antibody
NBP2-49214
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
MBTPS1 Antibody (2E6)
MBTPS1 Antibody (2E6)
H00008720-M07
Species: Hu
Applications: ELISA, ICC/IF
Host: Mouse Monoclonal
Lysates
MBTPS1 Overexpression Lysate ...
MBTPS1 Overexpression Lysate (Native)
NBL1-12936
Applications: WB
Proteins
MBTPS1 Partial Recombinant Pr ...
MBTPS1 Partial Recombinant Protein
H00008720-Q01
Species: Hu
Applications: WB, ELISA, PA
MBTPS1 Recombinant Protein
MBTPS1 Recombinant Protein
H00008720-P01
Species: Hu
Applications: WB, ELISA, PA
MBTPS1 Recombinant Protein An ...
MBTPS1 Recombinant Protein Antigen
NBP2-49214PEP
Species: Hu
Applications: AC
RNAi
MBTPS1 RNAi
MBTPS1 RNAi
H00008720-R02
Species: Hu
Applications: RNAi, RNAi SP
MBTPS1 RNAi
MBTPS1 RNAi
H00008720-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The encoded protein has a central role in the regulation of lipid metabolism in cells. It is a sterol-regulated subtilisin-like serine protease that cleaves ER membrane-bound sterol regulatory element-binding proteins (SREBPs), a reaction that initiates the two-step proteolytic process by which transcriptionally active fragments of SREBPs are released from the membrane for translocation to the nucleus. The gene product is an integral membrane ER protein, with the bulk located in the ER lumen. It is synthesized as an inactive preproprotein that is self-activated by an intramolecular cleavage that generates the mature protein. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 8720
Alternate Names
  • Subtilisin/kexin-isozyme 1
  • SKI1
  • Endopeptidase S1P
  • subtilisin/kexin isozyme-1
  • membrane-bound transcription factor protease, site 1
  • site-1 protease
  • PCSK8
  • SKI-1membrane-bound transcription factor site-1 protease
  • KIAA0091MGC138712
  • S1PMGC138711
  • EC 3.4.21.112
  • membrane-bound transcription factor peptidase, site 1

Pathways for MBTPS1

View related products by pathway and learn more about each of the pathways below.

Lactation
Parturition
Fibrinolysis
Pigmentation
Response To Alcohol
Receptor Recycling
Pathogenesis

PTMs for MBTPS1

Learn more about PTMs related to MBTPS1.

Cleavage

Bioinformatics Tool for MBTPS1

Discover related pathways, diseases and genes to MBTPS1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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