MBP-1 Products

Description

The protein encoded by this gene is the predominant constituent of the crystalline core of the eosinophil granule. High levels of the proform of this protein are also present in placenta and pregnancy serum, where it exists as a complex with several other proteins including pregnancy-associated plasma protein A (PAPPA), angiotensinogen (AGT), and C3dg. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	5553
Alternate Names	BMPG BMPGeosinophil major basic protein bone marrow proteoglycan bone-marrow proteoglycan EMBP MBP1 MBP-1 MBPeosinophil granule major basic protein MGC14537 natural killer cell activator PRG2 proteoglycan 2 preproprotein Proteoglycan 2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granulemajor basic protein)

Research Areas for MBP-1

Find related products by research area and learn more about each of the different research areas below.

Asthma
Immunology