MAG/Siglec-4a Products

Antibodies
MAG/Siglec-4a Antibody
MAG/Siglec-4a Antibody
NBP1-81817
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
MAG/Siglec-4a Antibody
MAG/Siglec-4a Antibody
AF538
Species: Rt
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
MAG/Siglec-4a Antibody (11842 ...
MAG/Siglec-4a Antibody (118423) [U...
MAB538
Species: Rt
Applications: WB, Neut
Host: Mouse Monoclonal
Lysates
MAG/Siglec-4a Overexpression ...
MAG/Siglec-4a Overexpression Lysat...
NBP2-08122
Species: Hu
Applications: WB
MAG/Siglec-4a Overexpression ...
MAG/Siglec-4a Overexpression Lysat...
H00004099-T01
Species: Hu
Applications: WB
Proteins
Recombinant Rat MAG/Siglec-4a ...
Recombinant Rat MAG/Siglec-4a Fc C...
538-MG
Species: Rt
Applications: BA
Recombinant Human MAG/Siglec- ...
Recombinant Human MAG/Siglec-4a Pr...
H00004099-P01
Species: Hu
Applications: WB, ELISA, PA, PAGE
Recombinant Mouse MAG/Siglec- ...
Recombinant Mouse MAG/Siglec-4a Fc...
8580-MG
Species: Mu
Applications: BA

Description

Myelin-associated glycoprotein (MAG), a membrane glycoprotein of 100 kDa, is thought to be involved in the process of myelination (1). Axonal regeneration in the adult central nervous system (CNS) is limited by two proteins in myelin, Nogo and MAG (2). MAG has been implicated in inhibition of nerve regeneration in the CNS. This results from interactions between MAG and the Nogo receptor and gangliosides on the apposing axon, which generates intracellular inhibitory signals in the neuron (3). Results also suggest that MAG binds to a specific receptor and initiates a signal transduction cascade to effect inhibition. These results indicate that soluble dMAG detected in vivo could contribute to the lack of regeneration in the mammalian CNS after injury (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 4099
Alternate Names
  • SIGLEC4A
  • Siglec-4a
  • SIGLEC-4A
  • sialic acid-binding immunoglobulin-like lectin 4A
  • S-MAG
  • GMAsialic acid binding Ig-like lectin 4A
  • myelin-associated glycoprotein
  • myelin associated glycoprotein

Bioinformatics Tool for MAG/Siglec-4a

Discover related pathways, diseases and genes to MAG/Siglec-4a. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.