Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WB, Flow, CyTOF-ready, ICC/IFHost:
Cadherins are a multigene family of Ca++-dependent cell adhesion molecules. They are transmembrane glycoproteins consisting of an extracellular domain, which mediates Ca++-dependent intercellular adhesion by homophilic interactions, a transmembrane region and a cytoplasmic domain. The extracellular domain is divided into a series of subdomains designated EC1-EC5. Homolgies between different members of the cadherin family are most prominent in the cytoplasmic domain and in EC1 and EC2 and much less so in EC5 of the extracellular domain and in the transmembrane region. The binding properties and specificities of the adhesive function are located in the N-terminal part of the molecules. Four members of the cadherin family have been identified and molecularly cloned from mammalian cells. These include the neuronal (N), epithelial (E), placental (P) and muscle (M) cadherins. M-cadherin is not found in fibroblasts but is expressed at low level in myoblasts and is upregulated following induction of myotube formation, suggesting a specific function in skeletal muscle cell differentiation.
|Product By Gene ID
- cadherin 15, M-cadherin (myotubule)
- Muscle cadherin
- cadherin 15, type 1, M-cadherin (myotubule)
PTMs for M-Cadherin/Cadherin-15
Learn more about PTMs related to M-Cadherin/Cadherin-15.Methylation
Bioinformatics Tool for M-Cadherin/Cadherin-15
Discover related pathways, diseases and genes to M-Cadherin/Cadherin-15. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.