Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A Products

Description

JMJD2A is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor.

Bioinformatics

Entrez	9682 Human 230674 Mouse
Uniprot	NM_014663 Human CAH71021 Human O75164 Human O75449 Human Q8BW72 Mouse
Product By Gene ID	9682
Alternate Names	JmjC domain-containing histone demethylation protein 3A EC 1.14.11 jumonji domain containing 2A EC 1.14.11.- jumonji domain containing 2 JMJD2Alysine-specific demethylase 4A KIAA0677jumonji C domain-containing histone demethylase 3A JHDM3AJMJD2 Jumonji domain-containing protein 2A lysine (K)-specific demethylase 4A

Diseases related to Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A

Discover more about diseases related to Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A.

Malignant Neoplasms
Neoplasms
Mammary Neoplasms
Cell Transformation, Neoplastic
Malignant Neoplasm Of Breast
Neoplasm Invasiveness
Carcinoma
Cell Invasion
Cardiac Hypertrophy
Hypertrophy
Colonic Neoplasms
Malignant Neoplasm Of Lung
Left Ventricular Hypertrophy
Osteosarcoma
Malignant Neoplasm Of Prostate
Retinoblastoma
Leukemia
Autoimmunity
Instabilities, Chromosomal
Neoplasm Metastasis

Pathways for Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A

View related products by pathway and learn more about each of the pathways below.

Methylation
Demethylation
Histone Methylation
Cell Cycle
Cell Proliferation
Regulation Of Gene Expression
Gene Silencing
Dna Repair
Heterochromatin Organization
Cell Migration
Histone Modification
Oncogenesis
Histone Demethylation
Histone H3 Acetylation
Dna Replication
S Phase
Cell Growth
Pathogenesis
Cellular Senescence
Oxidative Demethylation

Research Areas for Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Epigenetics

PTMs for Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A

Learn more about PTMs related to Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A.

Methylation
Demethylation
Acetylation
Ubiquitination
Hydroxylation
Dephosphorylation

Bioinformatics Tool for Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A

Discover related pathways, diseases and genes to Lysine (K)-specific Demethylase 4A/KDM4A/JMJD2A. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.