LYK5 Products

Antibodies
LYK5 Antibody
LYK5 Antibody
NBP2-24700
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
LYK5 Antibody
LYK5 Antibody
NBP2-17187
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LYK5 Antibody (4E4)
LYK5 Antibody (4E4)
H00092335-M02
Species: Hu
Applications: WB, ELISA, IHC, IHC-P, PLA
Host: Mouse Monoclonal
Antibody Pairs
LYK5 Antibody Pair
LYK5 Antibody Pair
H00092335-PW1
Species: Hu
Applications: WB, IP
Lysates
LYK5 Overexpression Lysate (N ...
LYK5 Overexpression Lysate (Native)
NBP2-05254
Applications: WB
LYK5 Overexpression Lysate (D ...
LYK5 Overexpression Lysate (Denatu...
H00092335-T01
Applications: WB
Proteins
LYK5 Recombinant Protein Anti ...
LYK5 Recombinant Protein Antigen
NBP1-89577PEP
Species: Hu
Applications: AC
LYK5 Recombinant Protein
LYK5 Recombinant Protein
NBP2-51734
Species: Hu
Applications: PAGE
RNAi
LYK5 RNAi
LYK5 RNAi
H00092335-R07
Species: Hu
LYK5 RNAi
LYK5 RNAi
H00092335-R05
Species: Hu
LYK5 RNAi
LYK5 RNAi
H00092335-R06
Species: Hu

Description

The protein encoded by the LYK5 gene contains a STE20-like kinase domain, but lacks several residues that are critical forcatalytic activity, so it is termed a 'pseudokinase'. The protein forms a heterotrimeric complex withserine/threonine kinase 11 (STK11, also known as LKB1) and the scaffolding protein calcium binding protein 39 (CAB39,also known as MO25). The protein activates STK11 leading to the phosphorylation of both proteins and excluding STK11from the nucleus. The protein is necessary for STK11-induced G1 cell cycle arrest. A mutation in this gene has beenshown to result in polyhydramnios, megalencephaly, and symptomatic epilepsy (PMSE) syndrome. Multiple transcriptvariants encoding different isoforms have been found for this gene. Additional transcript variants have been describedbut their full-length nature is not known. (provided by RefSeq)

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 92335
Alternate Names
  • STE20-related kinase adapter protein alpha
  • STE20-related adapter protein
  • STE20-related adaptor protein
  • Serologically defined breast cancer antigen NY-BR-96
  • STE20-like pseudokinase
  • Stlk
  • protein kinase LYK5
  • NY-BR-96
  • STRADPMSE
  • LYK5FLJ90524
  • STRAD alpha
  • STE20-related kinase adaptor alpha

Pathways for LYK5

View related products by pathway and learn more about each of the pathways below.

Recombinational Repair
Cell Proliferation
Cell Death
Brain Development
Localization

Research Areas for LYK5

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for LYK5

Discover related pathways, diseases and genes to LYK5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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