Species: Mu
Applications: Flow
Host: Mouse Monoclonal
Species: Mu
Applications: Flow
Host: Mouse Monoclonal
Description
The monoclonal antibody HBF-719 reacts with the B6 allele of Ly49F, a member of the lectin-like homodimeric Ly49 family of cell surface receptors.1 Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on subpopulations of mouse CD8+ T cells. The HBF-719 antibody stains approx. 11% of NK1.1+CD3- splenocytes, and 3.5% (2.5 month old) to 10.0% (11 month old) of CD8+ spleen cells from C57BL/6 mice. (1)
Bioinformatics
| Product By Gene ID |
16637 |
| Alternate Names |
- Killer cell lectin like receptor 6
- Klra6
- Ly49F antigen
- Lymphocyte antigen 49F
- T cell surface glycoprotein Ly 49F
|
