Hu, Mu, Rt, Po, PmApplications:
WB, IB, ICC/IF, IHC, IHC-PHost:
WB, Simple Western, Flow, ICC/IF, IPHost:
Hu, Mu, RtApplications:
WB, Simple Western, ICC/IF, IHC, IHC-PHost:
Lysyl oxidase (LOX), a copper-containing amine oxidase, belongs to a heterogeneous family of enzymes that oxidize primary amine substrates to reactive aldehydes. LOX plays a vital role in the formation and repair of the extracellular matrix. In addition, LOX is a multifunctional enzyme having diverse biological functions such as developmental regulation, tumor suppression, cell motility, and cellular senescence. The secreted form of LOX is responsible for the invasive properties of hypoxic human cancer cells. Thus, Lysyl oxidase is essential for hypoxia-induced metastasis and is a good therapeutic target for preventing and treating metastases.
|Product By Gene ID
- protein-lysine 6-oxidase
- lysyl oxidaseEC 188.8.131.52
Bioinformatics Tool for LOX propeptide
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|LOX propeptide: A novel peptide cancer therapeutic
Lysyl oxidase, also known as LOX, is a copper-dependent enzyme that cross-links collagen and elastin through the oxidative deamination of peptidyl lysine (collagen and elastin) and hydroxylysine (collagen only) residues, thereby playing a critical rol... Read more.