Species: Hu
Applications: WB, IHC, B/N
Host: Goat Polyclonal
Species: Mu
Applications: WB, B/N
Host: Goat Polyclonal
Species: Hu
Applications: WB, Flow, B/N, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Mu
Applications: ELISA
Species: Rt
Applications: ELISA
Species: Hu
Applications: Binding Activity
Species: Mu
Applications: Binding Activity
Species: Hu
Applications: PAGE
Description
LOX 1 belongs to the C type lectin like protein super family. This unique scavenger receptor plays important roles in atherogenesis. Like other scavenger receptors, LOX 1 has a wide spectrum of physiological ligands, including OxLDL, anionic phospholipids, aged/apoptotic cells, activated platelets, and bacteria. The LOX 1 gene is a so called immediate early gene that is dynamically modulated by several factors in vitro and in vivo. LOX 1 expression is induced by stimuli such as inflammatory cytokines, OxLDL, TNF alpha, TGF beta, and ANG II in vitro, and several proatherogenic factors in vivo.
Bioinformatics
Uniprot |
Human Human Human Human Human Mouse |
Product By Gene ID |
4973 |
Alternate Names |
- CLEC8ASLOX1
- C-type lectin domain family 8 member A
- hLOX-1
- Lectin-like oxidized LDL receptor 1
- Lectin-like oxLDL receptor 1
- Lectin-type oxidized LDL receptor 1
- LOX-1
- LOX1ox LDL receptor 1
- LOXIN
- oxidised low density lipoprotein (lectin-like) receptor 1
- oxidized low density lipoprotein (lectin-like) receptor 1
- oxidized low-density lipoprotein receptor 1
- oxidized low-density lipoprotein receptor 1, soluble form
- Ox-LDL receptor 1
- SCARE1
- scavenger receptor class E, member 1
|