Lipin 3 Products

Antibodies
Lipin 3 Antibody
Lipin 3 Antibody
NBP2-31920
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lipin 3 Antibody
Lipin 3 Antibody
AF4064
Species: Mu
Applications: WB, ICC
Host: Goat Polyclonal
Lipin 3 Antibody (1D7)
Lipin 3 Antibody (1D7)
NBP2-45672
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
Lysates
Lipin 3 Overexpression Lysate ...
Lipin 3 Overexpression Lysate (Nat...
NBL1-12655
Applications: WB
Proteins
Lipin 3 Recombinant Protein A ...
Lipin 3 Recombinant Protein Antigen
NBP2-31920PEP
Species: Hu
Applications: AC

Description

Humans lipodystrophy is characterized by loss of body fat, fatty liver, hypertriglyceridemia, and insulin resistance. Mice carrying mutations in the fatty liver dystrophy (fld) gene have similar phenotypes. Through positional cloning, the mouse gene responsible for fatty liver dystrophy was isolated and designated Lpin1. The nuclear protein encoded by Lpin1 was named lipin. Lpin1 mRNA was expressed at high levels in adipose tissue and was induced during differentiation of preadipocytes. These results indicated that lipin is required for normal adipose tissue development and provided a candidate gene for human lipodystrophy. Through database searches, mouse and human EST and genomic sequences with similarities to Lpin1 were identified. These included two related mouse genes (Lpin2 and Lpin3) and three human homologs (LPIN1, LPIN2, and LPIN3). Human LPIN1 gene has been mapped to 2p25.; linkages of fat mass and serum leptin levels to this same region have been noted. Human LPIN2 and LPIN3 mapped to chromosomes 18p11 and 20q11-q12, respectively. The mouse genes encoding Lpin1, Lpin2, and Lpin3 mapped to chromosome 12, 17, and 2, respectively.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 64900
Alternate Names
  • Lipin-3-like
  • dJ450M14.3
  • Lipin-3
  • dJ450M14.2
  • EC 3.1.3.4
  • LIPN3L
  • phosphatidate phosphatase LPIN3
  • lipin 3-like
  • lipin-3
  • SMP2
  • dJ620E11.2
  • lipin 3

Diseases related to Lipin 3

Discover more about diseases related to Lipin 3.

Myalgia
Inflammation
Rhabdomyolysis
Inflammatory Response

Pathways for Lipin 3

View related products by pathway and learn more about each of the pathways below.

Immune Response
Localization
Inflammatory Response

Bioinformatics Tool for Lipin 3

Discover related pathways, diseases and genes to Lipin 3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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