LIM kinase 2 Products

Antibodies
LIM kinase 2 Antibody
LIM kinase 2 Antibody
NBP1-85783
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LIM kinase 2 [p Thr505] Antib ...
LIM kinase 2 [p Thr505] Antibody
NB100-82023
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
LIM kinase 2 Antibody
LIM kinase 2 Antibody
28670002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
LIM kinase 2 Overexpression L ...
LIM kinase 2 Overexpression Lysate...
H00003985-T01
Species: Hu
Applications: WB
LIM kinase 2 Overexpression L ...
LIM kinase 2 Overexpression Lysate...
NBL1-12538
Applications: WB
LIM kinase 2 Overexpression L ...
LIM kinase 2 Overexpression Lysate...
NBP2-06997
Applications: WB
Proteins
Recombinant Human LIM kinase ...
Recombinant Human LIM kinase 2 Pro...
H00003985-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human LIM kinase ...
Recombinant Human LIM kinase 2 Pro...
H00003985-P02
Species: Hu
Applications: WB, ELISA, PA
LIM kinase 2 Recombinant Prot ...
LIM kinase 2 Recombinant Protein A...
NBP1-85783PEP
Species: Hu
Applications: AC
RNAi
LIM kinase 2 RNAi
LIM kinase 2 RNAi
H00003985-R01
Species: Hu
Applications: RNAi, RNAi SP
LIM kinase 2 RNAi
LIM kinase 2 RNAi
H00003985-R06
Species: Hu
Applications: RNAi, RNAi SP
LIM kinase 2 RNAi
LIM kinase 2 RNAi
H00003985-R07
Species: Hu
Applications: RNAi, RNAi SP

Description

LIM-kinase 2 (LIMK2), a 75-kDa member of the LIM kinase family, is responsible for regulating actin polymerization via phosphorylation and inactivation of the actin depolymerizing factors ADF/cofilin (1). LIMK2 protein is found in the cytoplasm during interphase, redistributed to the mitotic spindle and then to the spindle midzone during anaphase to telophase (2). It has been shown that ROCK, a downstream protein kinase of Rho, activates LIMK2 by directly phosphorylates threonine 505 residue. Since activity of LIMK2 is cell cycle dependant, LIMK2 activity is markedly increased when HeLa cells are synchronized at mitosis with nocodazole treatment (3).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Human
Human
Human
Product By Gene ID 3985
Alternate Names
  • EC 2.7.11.1
  • LIMK-2
  • LIM domain kinase 2

Research Areas for LIM kinase 2

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
Phospho-Specific
Protein Kinase

PTMs for LIM kinase 2

Learn more about PTMs related to LIM kinase 2.

Phosphorylation
Dephosphorylation
Cleavage
Acetylation

Bioinformatics Tool for LIM kinase 2

Discover related pathways, diseases and genes to LIM kinase 2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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