WB, ELISA, ICC/IF, IPHost:
Applications: ELISA, Func
Applications: Func, PAGE, Bioactivity
Lactate dehydrogenase is also known as L-lactate dehydrogenase A chain, LDHA, LDH muscle subunit and LDH-M. Two isozymes of LDH occur in mammals, LDH-M and LDH-H which come together to form a homotetramer of 36 kDa subunits. Every LDH molecule consists of four subunits, where each subunit is either H or M (based on their electrophoretic properties.) There are, therefore, five LDH isotypes: LDH-1 (4H) -in the heart, LDH-2 (3H1M) -in the reticuloendothelial system, LDH-3 (2H2M) -in the lungs, LDH-4 (1H3M) -in the kidneys and LDH-5 (4M) -in the liver and striated muscle. Usually LDH-2 is the predominant form in the serum. An LDH-1 level higher than the LDH-2 level (a "flipped pattern") suggests myocardial infarction (damage to heart tissues releases heart LDH, which is rich in LDH-1, into the bloodstream). In general, LDH is often used as a marker of tissue breakdown. LDH shows a cytoplasmic localization.
|Product By Gene ID
- EC 1.1.1
- LDH heart subunit
- L-lactate dehydrogenase B chain
- Renal carcinoma antigen NY-REN-46
- EC 184.108.40.206
- lactate dehydrogenase B
Research Areas for Lactate Dehydrogenase
Find related products by research area and learn more about each of the different research areas below.HIF Target GenesHypoxia
Bioinformatics Tool for Lactate Dehydrogenase
Discover related pathways, diseases and genes to Lactate Dehydrogenase. Need help? Read the Bioinformatics Tool Guide
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