Ku70/XRCC6 Products

Description

The Ku autoantigen is a heterodimer of 70kDa (p70) and ~80kDa (p80) proteins. The p70/p80 dimer is important for function of a 460kDa DNAdependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Bioinformatics

Entrez	14375 Mouse 25019 Rat 2547 Human
Uniprot	AAH08343 Human AAH08343.1 Human AAH18259 Human NM_001469 Human NP_001460.1 Human P12956 Human Q6FG89 Human
Product By Gene ID	2547
Alternate Names	5'-deoxyribose-5-phosphate lyase Ku70 5'-dRP lyase Ku70 70 kDa subunit of Ku antigen ATP-dependent DNA helicase 2 subunit 1 ATP-dependent DNA helicase II 70 kDa subunit CTC box binding factor 75 kDa subunit CTC box-binding factor 75 kDa subunit CTC75 CTCBF D22S731 EC 3.6.4.- EC 4.2.99.- G22P1Ku70 Ku autoantigen p70 subunit Ku autoantigen, 70kDa KU70 ML8,70 kDa subunit thyroid-lupus autoantigen p70 Thyroid-lupus autoantigen TLAAD22S671 X-ray repair complementing defective repair in Chinese hamster cells 6DNA repair protein XRCC6 X-ray repair cross-complementing protein 6

Research Areas for Ku70/XRCC6

Find related products by research area and learn more about each of the different research areas below.

Breast Cancer
Cancer
DNA Double Strand Break Repair
DNA Repair
Non-homologous end-joining