Species: Hu
Applications: Flow, ICC/IF
Host: Rabbit Monoclonal
Species: Hu
Applications: Flow, ICC/IF, IP, MA
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Po, Bv, RM
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
KLF12 is a gene the codes for a protein that bonds to A32 in the AP-2-alpha gene promoter in order to facilitate the transcriptional repression to the AP-2-alpha gene. KLF12 has two isoforms, with lengths of 402 and 269 amino acids, and weights of approximately 44 and 28 kDa respectively. Current studies are being done on diseases and disorders relating to this gene, including Wegener's granulomatosis, rheumatoid arthritis, gastric cancer, pancreatic cancer, pancreatitis, and schizophrenia. KLF12 has also been shown to have interactions with EHMT2, CTBP1, and SIRT2.
Bioinformatics
| Entrez |
Human |
| Uniprot |
Human Human Human Human |
| Product By Gene ID |
11278 |
| Alternate Names |
- AP-2rep transcription factor
- AP-2rep
- AP2REPAP-2 repressor
- HSPC122
- KLF12 zinc finger transcriptional repressor
- Krueppel-like factor 12
- Kruppel-like factor 12
- Transcriptional repressor AP-2rep
|