Kininogen/Kininostatin/Bradykinin Products

Antibodies
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
AF1396
Species: Hu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
NB100-62405
Species: All
Applications: ELISA
Host: Rabbit Polyclonal
Antibody Pairs
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
H00003827-PW2
Species: Hu
Applications: WB, IP
ELISA Kits
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
KA1039
Species: Hu
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
KA1040
Species: Hu
Lysates
Kininogen/Kininostatin/Bradyk ...
Kininogen/Kininostatin/Bradykinin ...
H00003827-T03
Applications: WB

Description

Bradykinin is a nine amino acid vasoactive peptide which elicits numerous physiologic responses such as vasodilation, smooth muscle spasm and pain. Bradykinin is one of a family of such peptides called the kinins. These kinins are generated by proteolysis of high molecular weight precursors called kininogens upon activation by pathophysiologic conditions such as inflammation or allergy. The physiological actions of these kinins are brought about through their interaction with transmembrane receptors. There are two distinct bradykinin receptor subtypes; B1 and B2, both of which appear to be coupled to G-proteins. The B2 receptor subtype is found in healthy smooth muscle cells and neurons, whereas the B1 receptors are only detected following tissue injury. The B2 receptor is similar in structure to other seven helix G protein coupled receptors. Bradykinin has relatively low affinity for B1 receptors, interacting primarily with the B2 receptor through which several second messenger systems are stimulated, including inositol phospholipid hydrolysis, arachidonic acid metabolism, tyrosine phosphorylation, and membrane depolarization and hyperpolarization.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Product By Gene ID 3827
Alternate Names
  • kininogen-1
  • Williams-Fitzgerald-Flaujeac factor
  • bradykinin
  • High molecular weight kininogen
  • Fitzgerald factor
  • kininogen
  • Alpha-2-thiol proteinase inhibitor
  • KNGHMWK
  • BDK
  • kininogen 1

Pathways for Kininogen/Kininostatin/Bradykinin

View related products by pathway and learn more about each of the pathways below.

Coagulation
Glucose Homeostasis
Translation
Biological Regulation
Pathogenesis

Research Areas for Kininogen/Kininostatin/Bradykinin

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Immunology

Bioinformatics Tool for Kininogen/Kininostatin/Bradykinin

Discover related pathways, diseases and genes to Kininogen/Kininostatin/Bradykinin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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