KDELR1 Products

Antibodies
Lysates
KDELR1 Overexpression Lysate ...
KDELR1 Overexpression Lysate (Native)
NBL1-12220
Applications: WB
Proteins
KDELR1 Recombinant Protein
KDELR1 Recombinant Protein
H00010945-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
KDELR1 RNAi
KDELR1 RNAi
H00010945-R02
Species: Hu

Description

Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Mouse
Product By Gene ID 10945
Alternate Names
  • Putative MAPK-activating protein PM23
  • ER lumen protein retaining receptor 1
  • HDEL
  • PM23
  • ERD2
  • ERD2.1KDEL receptor 1
  • KDEL endoplasmic reticulum protein retention receptor 1
  • KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1

PTMs for KDELR1

Learn more about PTMs related to KDELR1.

Phosphorylation
Glycosylation
Cleavage
Ribosylation
Ubiquitination

Bioinformatics Tool for KDELR1

Discover related pathways, diseases and genes to KDELR1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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