Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Bv, GP, Rb
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: WB, ELISA, PA
Species: Hu
Applications: AC
Species: Hu
Applications: RNAi, RNAi SP
Description
K+ channels are divided into three subclasses, reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions, and include TASK, TREK, TRAAK and TWIK. TWIK-1 mRNA is expressed abundantly in brain and at lower levels in lung, kidney and skeletal muscle. The molecular weight of TWIK-1 in mouse brain is 40 kDa under reducing conditions. TWIK-2 shares low sequence homology with other mammalian family group members, and only 34% homology with TWIK-1. Human TWIK-2 is expressed in pancreas, placenta and heart, while mouse TWIK-2 is expressed in liver. TWIK-2 is inhibited by intracellular, but not extracellular, acidification.
Bioinformatics
| Entrez |
Human
Rat
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
3775 |
| Alternate Names |
- Potassium channel KCNO1
- HOHO1
- Inward rectifying potassium channel protein TWIK-1
- potassium inwardly-rectifying channel, subfamily K, member 1
- TWIK-1
- potassium channel subfamily K member 1
- K2p1.1
- K2P1
- DPK
- TWIK1HOHO
- KCNO1
- potassium channel, subfamily K, member 1
|
Bioinformatics Tool for KCNK1
Discover related pathways, diseases and genes to KCNK1. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
-Western Blot-NBL1-12176-img0002.jpg)
