Species: Hu, Mu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: AC
Description
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]. Transcript Variant: This variant (rom-k1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Bioinformatics
| Product By Gene ID |
3758 |
| Alternate Names |
- ATP-regulated potassium channel ROM-K
- ATP-sensitive inward rectifier potassium channel 1
- inwardly rectifying K+ channel
- KIR1.1
- potassium inwardly-rectifying channel, subfamily J, member 1
- ROMK1inwardly rectifying subfamily J member 1
|
