Jumonji/JARID2 Products

Description

Jumonji (JARID2) is a nuclear protein that participates in the negative regulation of cell growth. JARID2 is required for neural tube formation and is essential for normal heart development and function. In addition, Jumonji is a part of a group of proteins characterized by a novel structural motif, the JmjC domain, which is implicated in chromatin regulation through histone demethylation.

Bioinformatics

Entrez	3720 Human 16468 Mouse
Uniprot	NP_004964 Human NP_004964.2 Human Q92833 Human
Product By Gene ID	3720
Alternate Names	jumonji (mouse) homolog protein Jumonji Jumonji/ARID domain-containing protein 2 JMJjumonji-like protein jumonji homolog jumonji, AT rich interactive domain 2

Diseases related to Jumonji/JARID2

Discover more about diseases related to Jumonji/JARID2.

Neoplasms
Congenital Heart Defects
Myeloproliferative Disease
Malignant Neoplasms
Hypoplasia
Nervousness
Autistic Disorder
Autism Spectrum Disorders
Double Outlet Right Ventricle
Congenital Abnormality
Dysmyelopoietic Syndromes
Primary Myelofibrosis
Cell Transformation, Neoplastic
Schizophrenia
Retinoblastoma
Leukemia
Charge Syndrome
Disuse Muscle Atrophy
Cardiac Hypertrophy

Pathways for Jumonji/JARID2

View related products by pathway and learn more about each of the pathways below.

Methylation
Cell Cycle
Cell Proliferation
Heart Development
Cell Differentiation
Organ Development
Cell Growth
Neural Tube Closure
Tube Formation
Histone Modification
Liver Development
Histone Methylation
Mitosis
Localization
Tube Closure
Regulation Of Cell Proliferation
Neural Tube Formation
Pathogenesis
Germinal Center Formation
Cell Activation

Research Areas for Jumonji/JARID2

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
Chromatin Research
Epigenetics
Neuroscience
Transcription Factors and Regulators

PTMs for Jumonji/JARID2

Learn more about PTMs related to Jumonji/JARID2.

Methylation
Demethylation
Phosphorylation
Reduction

Bioinformatics Tool for Jumonji/JARID2

Discover related pathways, diseases and genes to Jumonji/JARID2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.