Intersectin 1 Products

Antibodies
Intersectin 1 Antibody
Intersectin 1 Antibody
NBP1-87806
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Intersectin 1 Antibody
Intersectin 1 Antibody
NB100-75281
Species: Hu
Applications: WB
Host: Chicken Polyclonal
Intersectin 1 Antibody
Intersectin 1 Antibody
NBP1-71832
Species: Hu, Ca, Ft, Mk, Pm, Sq
Applications: WB, IP
Host: Rabbit Polyclonal
Lysates
Intersectin 1 Overexpression ...
Intersectin 1 Overexpression Lysat...
NBP2-10857
Applications: WB
Proteins
Recombinant Human Intersectin ...
Recombinant Human Intersectin 1 Pr...
H00006453-Q01
Species: Hu
Applications: WB, ELISA, PA
Intersectin 1 Recombinant Pro ...
Intersectin 1 Recombinant Protein ...
NBP1-87806PEP
Species: Hu
Applications: AC
RNAi
Intersectin 1 RNAi
Intersectin 1 RNAi
H00006453-R02
Species: Hu
Applications: RNAi, RNAi SP
Intersectin 1 RNAi
Intersectin 1 RNAi
H00006453-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Intersectin 1 is an adapter protein that may provide an indirect link between the endocytic membrane traffic and the actin assembly machinery. It may regulate the formation of clathrin-coated vesicles. Isoform 1 could be involved in brain-specific synaptic vesicle recycling. Intersectin 1 is overexpressed in brain from Down syndrome foetuses suggesting a gene dosage-dependent contribution to the abnormalities of Down syndrome. Intersectin 1 interacts with dynamin, CDC42, SNAP25 and SNAP23. It clusters several dynamin in a manner that is regulated by alternative splicing. Intersectin 1 also binds clathrin-associated proteins and other components of the endocytic machinery, such as SPIN90, EPS15, EPN1, EPN2 and STN2. Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles. Isoform 1 could be involved in brain-specific synaptic vesicle recycling.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 6453
Alternate Names
  • Src homology 3 domain-containing protein
  • SH3 domain protein-1A
  • intersectin-1
  • SH3 domain-containing protein 1A
  • intersectin short variant 12
  • ITSN
  • 11
  • intersectin 1 (SH3 domain protein)

PTMs for Intersectin 1

Learn more about PTMs related to Intersectin 1.

Phosphorylation
Oxidation

Bioinformatics Tool for Intersectin 1

Discover related pathways, diseases and genes to Intersectin 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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