INSIG-2 Products

Antibodies
INSIG-2 Antibody
INSIG-2 Antibody
NBP1-59687
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
INSIG-2 Antibody
INSIG-2 Antibody
NBP1-60007
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
INSIG-2 Overexpression Lysate ...
INSIG-2 Overexpression Lysate (Nat...
NBL1-12004
Applications: WB
Proteins
Recombinant Human INSIG-2 Pro ...
Recombinant Human INSIG-2 Protein
H00051141-P01
Species: Hu
Applications: WB, ELISA, PA

Description

The protein encoded by the INSIG2 gene is highly similar to the protein product encoded by gene INSIG1. Both INSIG1 proteinand this protein are endoplasmic reticulum proteins that block the processing of sterol regulatory element bindingproteins (SREBPs) by binding to SREBP cleavage-activating protein (SCAP), and thus prevent SCAP from escorting SREBPsto the Golgi. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 51141
Alternate Names
  • insulin-induced gene 2 protein
  • insulin induced protein 2
  • INSIG2 membrane protein
  • MGC26273
  • INSIG-2
  • insulin induced gene 2

PTMs for INSIG-2

Learn more about PTMs related to INSIG-2.

Ubiquitination
Cleavage
Oxidation
Phosphorylation
Methylation
Geranylgeranylation

Bioinformatics Tool for INSIG-2

Discover related pathways, diseases and genes to INSIG-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related INSIG-2 Blog Posts

Check out the latest blog posts on INSIG-2.
SREBP: Gatekeeper of Cholesterol Homeostasis
SREBP1 (sterol-regulatory-element-binding protein 2) is a basic-helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor. It regulates sterol and cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g....    Read more.
Read more INSIG-2 related blogs.