IFIT2 Products

Antibodies
IFIT2 Antibody
IFIT2 Antibody
NBP1-31164
Species: Hu
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
IFIT2 Antibody
IFIT2 Antibody
NBP2-15180
Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
IFIT2 Antibody
IFIT2 Antibody
NBP1-85617
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
IFIT2 Antibody Pair
IFIT2 Antibody Pair
H00003433-PW1
Species: Hu
Applications: WB, IP
Lysates
IFIT2 Overexpression Lysate ( ...
IFIT2 Overexpression Lysate (Native)
NBL1-11835
Applications: WB
IFIT2 Overexpression Lysate ( ...
IFIT2 Overexpression Lysate (Denat...
H00003433-T01
Applications: WB
Proteins
IFIT2 Recombinant Protein
IFIT2 Recombinant Protein
H00003433-P01
Species: Hu
Applications: WB, ELISA, PA
IFIT2 Recombinant Protein Ant ...
IFIT2 Recombinant Protein Antigen
NBP1-85617PEP
Species: Hu
Applications: AC

Description

Saha et al. used this antibody to study protein expression of murine GARG39/IFIT2 in relation to viral infection. Immunofluorescence localized this protein in association with the mitotic spindle in both mitotically active normal NIH3T3 and B16F10 melanoma cells. Western blotting shows approx. 55 kD band GARG39/IFIT2 in brain tissue of mice infected with Japanese encephalitis virus (JEV). Brain tissue from non-infected mice did not display this band. In 1994 Bluyssen et al. characterized the gene for murine GARG39/IFIT2 and historically the protein has been identified as interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2), interferon-induced 54 kDa protein (IFI-54K), glucocorticoid-attenuated response gene 39 protein (GARG-39). Human IFIT2, with 62% amino acid sequence identity, has been referred to as Interferon-induced protein with tetratricopeptide repeats 2 (IFIT-2), Interferon-induced 54 kDa protein (IFI-54K) and ISG-54 K. Kang et al. showed with proteome analysis IFIT2 was expressed more than two-fold in human osteosarcoma cells U2OS treated with ascochlorin. Kawada et al. studied gene expression to show that IFIT2 is strongly upregulated in peripheral blood in children during the acute phase of influenza.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Mouse
Product By Gene ID 3433
Alternate Names
  • IFI-54K
  • P54
  • interferon-induced protein 54
  • cig42
  • Interferon, alpha-inducible protein (MW 54kD)
  • ISG-54K
  • ISG54
  • IFI-54
  • ISG-54 K
  • GARG-39
  • IFI54IFIT-2
  • G10P2IFI-54K
  • Interferon-induced 54 kDa protein
  • interferon-induced protein with tetratricopeptide repeats 2

PTMs for IFIT2

Learn more about PTMs related to IFIT2.

Phosphorylation
Methylation
Dephosphorylation

Bioinformatics Tool for IFIT2

Discover related pathways, diseases and genes to IFIT2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IFIT2 Blog Posts

Check out the latest blog posts on IFIT2.
STING in Innate Immunity and Cancer: What’s the Buzz About?
STING (STimulator of INterferon Genes protein) acts as a sensor of cytosolic DNA. Bacteria/Virus or self-derived DNA in the cytosol activates the STING pathway and promotes the production of type I interferons (IFN-alpha and IFN-beta). STING also...    Read more.
Read more IFIT2 related blogs.