IDH3B Products

Description

IDH3B codes for a protein that has three isoforms, with lengths of 385, 383, and 233 amino acids, and weights of 42, 42, and 26 kDa respectively, and is a protein that is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase, which localizes to the mitochondrial matrix. Current studies are being done on several diseases and disorders related to this gene, including retinitis pigmentosa, blindness, and ataxia. IDH3B has also been shown to have interactions with MAPK6, MYC, IDH3G, PHLDA3, and IDH3A in pathways such as the TCA cycle and metabolic pathways.

Bioinformatics

Entrez	170718 Mouse 3420 Human 94173 Rat
Uniprot	NP_008830 Human NP_008830.2 Human NP_008830.2 Human NP_008830.2 Human NP_777280.1 Human
Product By Gene ID	3420
Alternate Names	EC 1.1.1 EC 1.1.1.41 FLJ11043 H-IDHB isocitrate dehydrogenase [NAD] subunit beta, mitochondrial isocitrate dehydrogenase 3 (NAD+) beta isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit Isocitric dehydrogenase subunit beta MGC903 NAD(+)-specific ICDH subunit beta NAD+-specific ICDH NAD+-specific isocitrate dehydrogenase b subunit NAD+-specific isocitrate dehydrogenase beta RP46