IDH2 Products

Antibodies
Lysates
IDH2 Overexpression Lysate
IDH2 Overexpression Lysate
NBL1-11818
Species: Hu
Applications: WB
Proteins
IDH2 Antibody Blocking Peptid ...
IDH2 Antibody Blocking Peptide
NBP2-22166PEP
Species: Hu
Applications: AC
Recombinant Human IDH2 GST (N ...
Recombinant Human IDH2 GST (N-Term...
H00003418-P01
Species: Hu
Applications: WB, ELISA, PA, AP
Recombinant Human IDH2 GST (N ...
Recombinant Human IDH2 GST (N-Term...
H00003418-Q01
Species: Hu
Applications: WB, ELISA, PA, AP

Description

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 3418
Alternate Names
  • mNADP-IDH
  • NADP(+)-specific ICDH
  • isocitrate dehydrogenase [NADP], mitochondrial
  • IDP
  • IDHM
  • IDH
  • IDPM
  • ICD-M
  • D2HGA2
  • Oxalosuccinate decarboxylase
  • EC 1.1.1.42
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial

Bioinformatics Tool for IDH2

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