ID2 Products

Description

ID2 is encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.

Bioinformatics

Entrez	3398 Human
Uniprot	AAH30639 Human NM_002166 Human NP_002157 Human Q02363 Human
Product By Gene ID	3398
Alternate Names	BHLHB26 bHLHb26cell growth-inhibiting gene 8 Class B basic helix-loop-helix protein 26 DNA-binding protein inhibitor ID2 DNA-binding protein inhibitor ID-2 GIG8 helix-loop-helix protein ID2 ID2A ID2H inhibitor of differentiation 2 Inhibitor of DNA binding 2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein MGC26389

Research Areas for ID2

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Cancer