ICOS Products

Antibodies
ICOS Antibody (SP98)
ICOS Antibody (SP98)
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Monoclonal
ICOS Antibody (C398.4A)
ICOS Antibody (C398.4A)
NB100-77934
Species: Hu, Mu, Rt
Applications: Flow, IHC, IHC-Fr, IP
Host: Armenian Hamster Monoclonal
ICOS Antibody
ICOS Antibody
AF169
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
ICOS Overexpression Lysate (D ...
ICOS Overexpression Lysate (Denatu...
H00029851-T02
Applications: WB
Proteins
ICOS Recombinant Protein
ICOS Recombinant Protein
H00029851-P01
Species: Hu
Applications: WB, ELISA, PA
ICOS Recombinant Protein
ICOS Recombinant Protein
H00029851-G01
Species: Hu
RNAi
ICOS RNAi
ICOS RNAi
H00029851-R01
Species: Hu

Description

The C398.4A antibody reacts with the human, mouse and rat 47-57 kD ICOS protein, also known as inducible costimulatory molecule and H4. This protein is homologous to the CD28/CTLA-4 proteins. ICOS is expressed on activated T cells and a subset of thymocytes. It is able to costimulate T cells proliferation. In addition, ICOS is involved in humoral immune responses (B cell germinal center formation). The ICOS ligand is B7h/B7RP-1 or B7-H2. ICOS stimulation has been shown to potentiate TCR-mediated IL-4 and IL-10 production and has been proposed to play a role in Th2 cell development. The C398.4A antibody is useful for flow cytometric analysis and is able to costimulate T cell activation and proliferation.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 29851
Alternate Names
  • CD278 antigen
  • CVID1
  • inducible T-cell costimulator
  • Activation-inducible lymphocyte immunomediatory molecule
  • inducible costimulator
  • AILIMCD278
  • MGC39850
  • inducible T-cell co-stimulator

Bioinformatics Tool for ICOS

Discover related pathways, diseases and genes to ICOS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.