Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Applications: WB, ELISA
Host: Mouse Polyclonal
ICEBERG, also known as Caspase recruitment domain-containing protein 18, is a 90 amino acid protein that is 10 kDa, most often expressed in the heart and placenta, down-regulates the release of IL1B, and by interacting with caspase-1 and preventing its association with RIP2 inhibits the generation of IL-1-beta. This protein is being studied for its involvement in chronic lymphocytic leukemia. The ICEBERG protein has been linked to the NOD-like receptor signaling pathway where it interacts with CASP1, CARD8, CARD16, and CARD17.
|Product By Gene ID
- ICEBERG caspase-1 inhibitor
- ICEBERGcaspase recruitment domain-containing protein 18
- Caspase-1 inhibitor Iceberg
- caspase recruitment domain family, member 18
Research Areas for ICEBERG
Find related products by research area and learn more about each of the different research areas below.ApoptosisCancer
Bioinformatics Tool for ICEBERG
Discover related pathways, diseases and genes to ICEBERG. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.