ICEBERG Products

Antibodies
ICEBERG Antibody
ICEBERG Antibody
NBP2-48688
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
ICEBERG Antibody
ICEBERG Antibody
H00059082-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
ICEBERG Antibody
ICEBERG Antibody
NB120-3684
Species: Hu, Rt
Applications: WB, ELISA
Host: Rabbit Polyclonal
Lysates
ICEBERG Overexpression Lysate ...
ICEBERG Overexpression Lysate (Den...
H00059082-T01
Species: Hu
Applications: WB
ICEBERG Overexpression Lysate ...
ICEBERG Overexpression Lysate (Nat...
NBP2-06534
Applications: WB
Proteins
ICEBERG Recombinant Protein A ...
ICEBERG Recombinant Protein Antigen
NBP2-48688PEP
Species: Hu
Applications: AC
ICEBERG Recombinant Protein
ICEBERG Recombinant Protein
NBP1-98862
Species: Hu
Applications: PAGE

Description

ICEBERG, also known as Caspase recruitment domain-containing protein 18, is a 90 amino acid protein that is 10 kDa, most often expressed in the heart and placenta, down-regulates the release of IL1B, and by interacting with caspase-1 and preventing its association with RIP2 inhibits the generation of IL-1-beta. This protein is being studied for its involvement in chronic lymphocytic leukemia. The ICEBERG protein has been linked to the NOD-like receptor signaling pathway where it interacts with CASP1, CARD8, CARD16, and CARD17.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 59082
Alternate Names
  • pseudo-ICE
  • ICEBERG caspase-1 inhibitor
  • UNQ5804
  • ICEBERGcaspase recruitment domain-containing protein 18
  • Caspase-1 inhibitor Iceberg
  • caspase recruitment domain family, member 18

Research Areas for ICEBERG

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer

Bioinformatics Tool for ICEBERG

Discover related pathways, diseases and genes to ICEBERG. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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