Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Pm, Rb, Xp, Ze
Applications: WB, Simple Western, ICC/IF, IHC, KO
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt, Ze
Applications: WB, IHC, IP
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, ELISA, Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: PAGE
Species: Hu
Applications: AC
Description
HPRT is encoded by this gene is a transferase, which catalyzes conversion of hypoxanthine to inosine monophosphate and guanine to guanosine monophosphate via transfer of the 5-phosphoribosyl group from 5-phosphoribosyl 1-pyrophosphate. This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway. Mutations in this gene result in Lesch-Nyhan syndrome or gout.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Mouse
|
| Product By Gene ID |
3251 |
| Alternate Names |
- EC 2.4.2.8
- HGPRTHPRTHGPRTase
- hypoxanthine phosphoribosyltransferase 1
- hypoxanthine-guanine phosphoribosyltransferase
|
Research Areas for HPRT
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism
![Enzyme Activity HPRT [Unconjugated]](http://images.novusbio.com/fullsize2/HPRT_10314HP_2923.jpg)
![SDS-PAGE HPRT [Unconjugated]](http://images.novusbio.com/fullsize2/HPRT_10314HP_2922.jpg)