HMBS Products

Antibodies
HMBS Antibody
HMBS Antibody
NBP2-33600
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HMBS Antibody (3F4)
HMBS Antibody (3F4)
NBP2-45976
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
HMBS Antibody
HMBS Antibody
NBP1-87329
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
HMBS Antibody Pair
HMBS Antibody Pair
H00003145-AP21
Species: Hu
Applications: S-ELISA
HMBS Antibody Pair
HMBS Antibody Pair
H00003145-AP11
Species: Hu
Applications: S-ELISA
Lysates
HMBS Overexpression Lysate (D ...
HMBS Overexpression Lysate (Denatu...
H00003145-T01
Species: Hu
Applications: WB
HMBS Overexpression Lysate (N ...
HMBS Overexpression Lysate (Native)
NBL1-11604
Applications: WB
Proteins
HMBS Recombinant Protein Anti ...
HMBS Recombinant Protein Antigen
NBP2-33600PEP
Species: Hu
Applications: AC
HMBS Recombinant Protein Anti ...
HMBS Recombinant Protein Antigen
NBP1-87329PEP
Species: Hu
Applications: AC
HMBS Recombinant Protein
HMBS Recombinant Protein
NBP1-99086
Species: Hu
Applications: PAGE
RNAi
HMBS RNAi
HMBS RNAi
H00003145-R02
Species: Hu
HMBS RNAi
HMBS RNAi
H00003145-R01
Species: Hu

Description

HMBS encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 3145
Alternate Names
  • uroporphyrinogen I synthase
  • uroporphyrinogen I synthetase
  • porphyria, acute; Chester type
  • PORC
  • porphobilinogen deaminase
  • UPSEC 2.5.1.61
  • PBGDPBG-D
  • hydroxymethylbilane synthasePre-uroporphyrinogen synthase

Research Areas for HMBS

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research

PTMs for HMBS

Learn more about PTMs related to HMBS.

Reduction
Oxidation

Bioinformatics Tool for HMBS

Discover related pathways, diseases and genes to HMBS. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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