HLA DQB1 Products

Antibodies
HLA DQB1 Antibody
HLA DQB1 Antibody
NBP1-84549
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
HLA DQB1 Antibody
HLA DQB1 Antibody
H00003119-B01P
Species: Hu
Applications: WB, Flow
Host: Mouse Polyclonal
HLA DQB1 Antibody (1G6)
HLA DQB1 Antibody (1G6)
H00003119-M02
Species: Hu
Applications: WB, ELISA, S-ELISA
Host: Mouse Monoclonal
Lysates
HLA DQB1 Overexpression Lysat ...
HLA DQB1 Overexpression Lysate
NBP2-10780
Species: Hu
Applications: WB
Proteins
Recombinant Human HLA DQB1 GS ...
Recombinant Human HLA DQB1 GST (N-...
H00003119-Q01
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
Recombinant Human HLA DQB1 GS ...
Recombinant Human HLA DQB1 GST (N-...
H00003119-P02
Species: Hu
Applications: WB, ELISA, PA, PAGE, AP
HLA DQB1 Recombinant Protein ...
HLA DQB1 Recombinant Protein Antigen
NBP1-84549PEP
Species: Hu
Applications: AC

Description

HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3119
Alternate Names
  • MHC class II DQA1
  • DC-1 alpha chain
  • HLA-DCA
  • DC-alpha
  • HLA class II histocompatibility antigen, DQ alpha 1 chain-like

Research Areas for HLA DQB1

Find related products by research area and learn more about each of the different research areas below.

Asthma
Diabetes Research
Immunology

PTMs for HLA DQB1

Learn more about PTMs related to HLA DQB1.

Cleavage
Citrullination
Methylation

Bioinformatics Tool for HLA DQB1

Discover related pathways, diseases and genes to HLA DQB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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