HLA DQB1 Products

Antibodies
HLA DQB1 Antibody
HLA DQB1 Antibody
NBP1-84549
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HLA DQB1 Antibody
HLA DQB1 Antibody
H00003119-B01P
Species: Hu
Applications: WB, Flow
Host: Mouse Polyclonal
Antibody Pairs
HLA DQB1 Antibody Pair
HLA DQB1 Antibody Pair
H00003119-PW1
Species: Hu
Applications: WB, IP
Lysates
HLA DQB1 Overexpression Lysat ...
HLA DQB1 Overexpression Lysate (De...
H00003119-T01
Species: Hu
Applications: WB
HLA DQB1 Overexpression Lysat ...
HLA DQB1 Overexpression Lysate (Na...
NBP2-10780
Applications: WB
Proteins
Recombinant Human HLA DQB1 Pr ...
Recombinant Human HLA DQB1 Protein
H00003119-P02
Species: Hu
Applications: WB, ELISA, PA
HLA DQB1 Recombinant Protein ...
HLA DQB1 Recombinant Protein Antigen
NBP1-84549PEP
Species: Hu
Applications: AC
HLA DQB1 Partial Protein
HLA DQB1 Partial Protein
H00003119-Q01
Species: Hu
Applications: WB, ELISA, PA
RNAi
HLA DQB1 RNAi
HLA DQB1 RNAi
H00003119-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HLA-DQB1 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and it contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3119
Alternate Names
  • MHC class II DQA1
  • DC-1 alpha chain
  • HLA-DCA
  • DC-alpha
  • HLA class II histocompatibility antigen, DQ alpha 1 chain-like

Research Areas for HLA DQB1

Find related products by research area and learn more about each of the different research areas below.

Asthma
Diabetes Research
Immunology

PTMs for HLA DQB1

Learn more about PTMs related to HLA DQB1.

Cleavage
Citrullination
Methylation

Bioinformatics Tool for HLA DQB1

Discover related pathways, diseases and genes to HLA DQB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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