Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse monoclonal
Species: Hu
Applications: WB, Flow, ICC/IF, MS
Host: Rabbit Monoclonal
Species: Hu
Applications: WB, Flow, ICC/IF, MS
Host: Rabbit Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: AC
Description
hHR23b is encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.
Bioinformatics
| Product By Gene ID |
5887 |
| Alternate Names |
- HHR23B
- HR23BUV excision repair protein RAD23 homolog B
- P58
- RAD23 (S. cerevisiae) homolog B
- RAD23 homolog B (S. cerevisiae)
- RAD23, yeast homolog of, B
- XP-C repair complementing complex 58 kDa
- XP-C repair complementing protein
- XP-C repair-complementing complex 58 kDa protein
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