hHR23b Products

Description

hHR23b is encoded by this gene is one of two human homologs of Saccharomyces cerevisiae Rad23, a protein involved in the nucleotide excision repair (NER). This protein was found to be a component of the protein complex that specifically complements the NER defect of xeroderma pigmentosum group C (XP-c) cell extracts in vitro. This protein was also shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, and thus this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.

Bioinformatics

Entrez	19359 Mouse 298012 Rat 5887 Human
Uniprot	AAH20973 Human AAH20973.1 Human NM_002874 Human NP_002865 Human NP_002865.1 Human P54727 Human
Product By Gene ID	5887
Alternate Names	hHR23B HHR23B HR23BUV excision repair protein RAD23 homolog B P58 p58 RAD23 (S. cerevisiae) homolog B RAD23 homolog B (S. cerevisiae) RAD23, yeast homolog of, B XP-C repair complementing complex 58 kDa XP-C repair complementing protein XP-C repair-complementing complex 58 kDa protein

Research Areas for hHR23b

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Core ESC-Like Genes
DNA Repair
Nucleotide Excision Repair
Stem Cell Markers
Tumor Suppressors