HEXB Products

Antibodies
HEXB Antibody
HEXB Antibody
NBP2-49211
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
HEXB Antibody
HEXB Antibody
NBP2-48689
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
HEXB Antibody
HEXB Antibody
H00003074-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Lysates
HEXB Overexpression Lysate (D ...
HEXB Overexpression Lysate (Denatu...
H00003074-T01
Species: Hu
Applications: WB
HEXB Overexpression Lysate (N ...
HEXB Overexpression Lysate (Native)
NBL1-11516
Applications: WB
Proteins
Recombinant Human HEXB Protei ...
Recombinant Human HEXB Protein
H00003074-P01
Species: Hu
Applications: WB, ELISA, PA
HEXB Recombinant Protein Anti ...
HEXB Recombinant Protein Antigen
NBP2-49211PEP
Species: Hu
Applications: AC
HEXB Recombinant Protein Anti ...
HEXB Recombinant Protein Antigen
NBP2-48689PEP
Species: Hu
Applications: AC

Description

HEXB, also known as Beta-hexosaminidase subunit beta, is a 556 amino acid that is 63 kDa, lysosome located, composed of two subunits, alpha and beta, which are encoded by separate gene, and in control of the degradation of GM2 gangliosides and other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. Current research is being performed on several diseases and disorders including gangliosidosis, sandhoff disease, infantile, juvenile, and adult forms, tay-sachs disease, neuronitis, lysosomal storage disease, motor neuron disease, cervical cancer, mucopolysaccharidosis, cervicitis, neurodegenerative disease, recurrent respiratory papillomatosis, hairy cell leukemia, macrocephaly, autonomic dysfunction, cholesteatoma, type 2 diabetes mellitus, rheumatoid arthritis, and diarrhea. The protein has been linked to pathways such as glycan degradation, amino sugar and nucleotide sugar metabolism, glycosaminoglycan degradation, glycosphingolipid biosynthesis - globo series, glycosphingolipid biosynthesis - ganglio series, MPS VI - Maroteaux-Lamy syndrome, metabolic pathways, and lysosome pathways where it interacts with EIF2D, GYG1, CSNK2B, CHIA,CHIT1, and CHIT1 proteins.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3074
Alternate Names
  • beta-hexosaminidase subunit beta
  • HCC-7
  • Hexosaminidase subunit B
  • ENC-1AS
  • Cervical cancer proto-oncogene 7 protein
  • EC 3.2.1.52
  • Beta-N-acetylhexosaminidase subunit beta
  • N-acetyl-beta-glucosaminidase subunit beta
  • hexosaminidase B (beta polypeptide)

Research Areas for HEXB

Find related products by research area and learn more about each of the different research areas below.

Neurodegeneration

PTMs for HEXB

Learn more about PTMs related to HEXB.

Glycosylation
Phosphorylation
Cleavage
Methylation
Deglycosylation

Bioinformatics Tool for HEXB

Discover related pathways, diseases and genes to HEXB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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