Species: Hu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Monoclonal
Applications: WB, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
WB, ELISA, PA, AP
Applications: RNAi, RNAi SP
The product encoded by this gene is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity. Mutations in this gene cause hemochromatosis type 2B, also known as juvenile hemochromatosis, a disease caused by severe iron overload that results in cardiomyopathy, cirrhosis, and endocrine failure.
|Product By Gene ID
- HEPCPutative liver tumor regressor
- Liver-expressed antimicrobial peptide 1
- hepcidin antimicrobial peptide
Bioinformatics Tool for Hepcidin Antimicrobial Peptide
Discover related pathways, diseases and genes to Hepcidin Antimicrobial Peptide. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.