Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1 Products

Description

HS6ST1 (Heparan-sulphate 6-O-sulfotransferase 1) is a single-pass type II transmembrane protein that catalyses the transfer of sulphate from PAPS (3'-phosphoadenosine 5'-phosphosulphate) to position 6 of the N-sulphoglucosamine residue of heparan sulphate. It is expressed in foetal brain and liver and is thought to play a significant role in axonal guidance through sulphation of heparan sulphate proteoglycans, with HS6ST1 expression mirroring that of Slit1 and Slit2.

Bioinformatics

Entrez	9394 Human
Uniprot	NP_004798 Human NP_004798.3 Human
Product By Gene ID	9394
Alternate Names	MGC116899 EC 2.8.2 FLJ25392 EC 2.8.2.- DKFZp547H098 heparan-sulfate 6-sulfotransferase HS6ST-1 HS6STheparan-sulfate 6-O-sulfotransferase 1 MGC116901 heparan sulfate 6-O-sulfotransferase 1

Diseases related to Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1

Discover more about diseases related to Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1.

Tissue Adhesions
Malignant Neoplasms
Neoplasms
Cytogenetic Abnormality
Hypogonadotropic Hypogonadism
Kallmann Syndrome
Exostoses
Growth Retardation
Hypogonadism
Disease Of Adrenal Medulla
Premature Menopause
Tumor Progression
Anosmia
Bone Neoplasms
Infertility
Bilateral Cleft Lip
Hypokinesia
Carcinoma
Tumor Angiogenesis
Chondrosarcoma

Pathways for Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1

View related products by pathway and learn more about each of the pathways below.

Sulfation
Axon Guidance
Gland Development
Lacrimal Gland Development
Secretion
Cell Adhesion
Centromere Separation
Secretory Pathway
Muscle Contraction
Menopause
Cell-matrix Adhesion
Neuron Development
Vasculogenesis
Embryo Development
Neuron Migration
Angiogenesis
Trachea Formation
Corpus Callosum Development
Innervation
Rna Interference

PTMs for Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1

Learn more about PTMs related to Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1.

Sulphation
Acetylation
Deacetylation

Bioinformatics Tool for Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1

Discover related pathways, diseases and genes to Heparan Sulfate 6-O-Sulfotransferase 1/HS6ST1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.