HB-EGF Products

Antibodies
HB-EGF Antibody
HB-EGF Antibody
AF-259-NA
Species: Hu
Applications: WB, IHC, ELISA(Cap), Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
HB-EGF Antibody
HB-EGF Antibody
AF8239
Species: Mu
Applications: WB, IHC
Host: Sheep Polyclonal
HB-EGF Antibody (406316)
HB-EGF Antibody (406316)
MAB2591
Species: Hu
Applications: WB, Neut
Host: Mouse Monoclonal
Lysates
HB-EGF Overexpression Lysate ...
HB-EGF Overexpression Lysate (Native)
NBL1-11459
Applications: WB
Proteins
Mouse HB-EGF Protein
Mouse HB-EGF Protein
NBP2-35069
Species: Mu
Applications: Func, PAGE
Rat HB-EGF Protein
Rat HB-EGF Protein
NBP2-35210
Species: Rt
Applications: Func, PAGE
Human HB-EGF Protein
Human HB-EGF Protein
NBP2-34920
Species: Hu
Applications: Func, PAGE
RNAi
HB-EGF RNAi
HB-EGF RNAi
H00001839-R02
Species: Hu

Description

HB-EGF is an EGF related growth factor that signals through the EGF receptor, and stimulates the proliferation of smooth muscle cells (SMC), fibroblasts, epithelial cells, and keratinocytes. HB-EGF is expressed in numerous cell types and tissues, including vascular endothelial cells and SMC, macrophages, skeletal muscle, keratinocytes, and certain tumor cells. The ability of HB-EGF to specifically bind heparin and heparin sulfate proteoglycans is distinct from other EGF-like molecules, and may be related to the enhanced mitogenic activity, relative to EGF, that HB-EGF exerts on smooth muscle cells. The human HB-EGF gene encodes a 208 amino acid transmembrane protein, which can be proteolytically cleaved to produce soluble HB-EGF. Recombinant human HB-EGF is a 9.7 kDa protein containing 86 amino acid residues, corresponding to the extra-cellular EGF-like and heparin binding domains of the full length HB-EGF protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 1839
Alternate Names
  • proheparin-binding EGF-like growth factor
  • DTS
  • heparin-binding epidermal growth factor
  • diphtheria toxin receptor (heparin-binding epidermal growth factor-like growthfactor)
  • DTRHEGFLdiphtheria toxin receptor (heparin-binding EGF-like growth factor)
  • DTSF
  • heparin-binding EGF-like growth factor

Research Areas for HB-EGF

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins

PTMs for HB-EGF

Learn more about PTMs related to HB-EGF.

Phosphorylation
Cleavage
Glycosylation
Oxidation

Bioinformatics Tool for HB-EGF

Discover related pathways, diseases and genes to HB-EGF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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