HAAO Products

Antibodies
HAAO Antibody
HAAO Antibody
NBP1-77361
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
HAAO Antibody
HAAO Antibody
NBP1-85892
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
HAAO Antibody
HAAO Antibody
NBP2-48755
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HAAO Overexpression Lysate (N ...
HAAO Overexpression Lysate (Native)
NBL1-11431
Applications: WB
Proteins
HAAO Recombinant Protein Anti ...
HAAO Recombinant Protein Antigen
NBP1-85892PEP
Species: Hu
Applications: AC
HAAO Recombinant Protein Anti ...
HAAO Recombinant Protein Antigen
NBP2-48755PEP
Species: Hu
Applications: AC
HAAO Recombinant Protein
HAAO Recombinant Protein
NBP1-98968
Species: Hu
Applications: PAGE
RNAi
HAAO RNAi
HAAO RNAi
H00023498-R01
Species: Hu

Description

3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. HAAO has been suggested to play a role in disorders associated with altered tissue levels of QUIN. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 23498
Alternate Names
  • 3-hydroxyanthranilic acid dioxygenase
  • HAO
  • EC 1.13.11.6,3-hydroxyanthranilate oxygenase
  • 3-HAO
  • HAD
  • 3-hydroxyanthranilate 3,4-dioxygenase

Pathways for HAAO

View related products by pathway and learn more about each of the pathways below.

Methylation
Gene Silencing
Dna Methylation

Research Areas for HAAO

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Lipid and Metabolism

PTMs for HAAO

Learn more about PTMs related to HAAO.

Methylation

Bioinformatics Tool for HAAO

Discover related pathways, diseases and genes to HAAO. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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