HA95/AKAP8L Products

Antibodies
HA95/AKAP8L Antibody
HA95/AKAP8L Antibody
NBP1-79140
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
HA95/AKAP8L Antibody
HA95/AKAP8L Antibody
NB100-61606
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
HA95/AKAP8L Antibody
HA95/AKAP8L Antibody
NBP2-47441
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
HA95/AKAP8L Overexpression Ly ...
HA95/AKAP8L Overexpression Lysate ...
NBL1-07430
Applications: WB
Proteins
HA95/AKAP8L Recombinant Prote ...
HA95/AKAP8L Recombinant Protein An...
NBP2-47440PEP
Species: Hu
Applications: AC
HA95/AKAP8L Recombinant Prote ...
HA95/AKAP8L Recombinant Protein An...
NBP2-47441PEP
Species: Hu
Applications: AC
RNAi
HA95/AKAP8L RNAi
HA95/AKAP8L RNAi
H00026993-R01
Species: Hu

Description

AKAP8L/HA95 is a PKA anchoring protein that is localized to the nuclear envelope and associates with chromatin upon nuclear envelope breakdown during mitosis. AKAP8L/HA95 has been found to play an important role in the initiation of DNA replication and may function as a scaffold for proteins such as MCM2 and LAP2beta. Additionally, AKAP8L/HA95 has been shown to co-locate with the PKA C subunit in splicing factor compartments and is involved in the regulation of pre-mRNA splicing. Further support for a scaffolding and splicing role in the nucleus comes from the observation that AKAP8L/HA95 colocalizes with HypA, a splicing-like factor, and through this association may function as a docking site for the nuclear accumulation of Huntington protein as seen in Huntington's disease.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 26993
Alternate Names
  • HRIHFB2018
  • NAKAP
  • HA95
  • Neighbor of AKAP95
  • neighbor of A kinase anchoring protein 95
  • Neighbor of A-kinase-anchoring protein 95
  • helicase A-binding protein 95 kDa
  • Homologous to AKAP95 protein
  • NAKAP95 A-kinase anchor protein 8-like
  • HAP95 DKFZp434L0650
  • AKAP8-like protein
  • A kinase (PRKA) anchor protein 8-like

Research Areas for HA95/AKAP8L

Find related products by research area and learn more about each of the different research areas below.

Chromatin Research
DNA Repair
DNA replication, Transcription, Translation and Splicing
Neuroscience

PTMs for HA95/AKAP8L

Learn more about PTMs related to HA95/AKAP8L.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for HA95/AKAP8L

Discover related pathways, diseases and genes to HA95/AKAP8L. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related HA95/AKAP8L Blog Posts

Check out the latest blog posts on HA95/AKAP8L.
HA95: Regulator of Nuclear Envelope Dynamics
HA95 is a nuclear protein with high homology to the nuclear A-kinase anchoring protein AKAP95, involved in the regulation of nuclear envelope-chromatin interactions. Antibody immunostaining data indicate that HA95 is tightly associated with chromatin...    Read more.
Read more HA95/AKAP8L related blogs.