GSK-3 alpha Products

Antibodies
GSK-3 alpha Antibody
GSK-3 alpha Antibody
NB100-81943
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
GSK-3 alpha [p Ser21] Antibod ...
GSK-3 alpha [p Ser21] Antibody
AF4125
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
GSK-3 alpha Antibody
GSK-3 alpha Antibody
NBP1-87445
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GSK-3 alpha Overexpression Ly ...
GSK-3 alpha Overexpression Lysate ...
NBL1-11361
Applications: WB
Proteins
GSK-3 alpha Recombinant Prote ...
GSK-3 alpha Recombinant Protein An...
NBP1-87445PEP
Species: Hu
Applications: AC
Recombinant Human GSK-3 alpha ...
Recombinant Human GSK-3 alpha Protein
P4182
Species: Hu
Applications: Func, PAGE
Recombinant Human GSK-3 alpha ...
Recombinant Human GSK-3 alpha Protein
NBP1-99200
Species: Hu
RNAi
GSK-3 alpha RNAi
GSK-3 alpha RNAi
H00002931-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Glycogen synthases kinase 3 alpha (GSK3-alpha) is a multifunctional Serine/Threonine protein kinase, one of two isoforms of GSK3 (1). Originally identified as a regulator of glycogen synthase, it has been shown to be involved in the hormonal control of several regulatory factors and transcription factors. GSK3-alpha activity is down regulated by phosphorylation on Serine 21 by PKB, or activated by phosphorylation on Tyrosine 279 (2). Insulin inactivates GSK3-alpha by rapid phosphorylation which leads to activation of Glycogen Synthase in the cells (3). GSK3-alpha activitiy has been linked to a pathogenic mechanism in Alzheimer's disease (4).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2931
Alternate Names
  • DKFZp686D0638
  • EC 2.7.11
  • EC 2.7.11.26
  • glycogen synthase kinase-3 alpha
  • GSK-3 alpha
  • glycogen synthase kinase 3 alpha

Research Areas for GSK-3 alpha

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Hypoxia
Phospho-Specific
Protein Kinase
Signal Transduction
Stem Cell Markers

PTMs for GSK-3 alpha

Learn more about PTMs related to GSK-3 alpha.

Phosphorylation

Bioinformatics Tool for GSK-3 alpha

Discover related pathways, diseases and genes to GSK-3 alpha. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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