GRK2 Products

Description

Adrenergic Receptor beta Kinase 1 (ADRBK1), also known as GRK2, is a member of the G-protein receptor kinase family. A ubiquitous cytosolic enzyme, GRK-2 specifically phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed under high agonist concentrations. Defects in GRK2 coupling with G-protein receptors may lead to heart failure.

Bioinformatics

Entrez	110355 Mouse 156 Human 25238 Rat
Uniprot	AAH37963.1 Human NP_001610 Human P25098 Human
Product By Gene ID	156
Alternate Names	adrenergic, beta, receptor kinase 1 BARK BARK1beta-ARK-1 BETA-ARK1 Beta-ARK-1 EC 2.7.11 EC 2.7.11.15 FLJ16718 G-protein coupled receptor kinase 2 GRK2beta-adrenergic receptor kinase 1

Research Areas for GRK2

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cellular Markers
Mitochondrial Markers
Neuroscience
Phospho-Specific
Protein Kinase
Signal Transduction

Related GRK2 Blog Posts

Check out the latest blog posts on GRK2.

"Freeze!" - Arrestin Antibodies Used in New Serotonin Syndrome Study The beta-arrestin family regulate receptor binding of G-proteins, a group of seven transmembrane receptor proteins which includes the adrenergic, dopamine and serotonin receptors. Recently, arrestin antibodies were used in a study into Serotonin Syndr...    Read more.

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