Granzyme H Products

Antibodies
Granzyme H Antibody
Granzyme H Antibody
AF1377
Species: Hu
Applications: WB, IP, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Granzyme H Antibody (185813)
Granzyme H Antibody (185813)
MAB1377
Species: Hu
Applications: WB
Host: Mouse Monoclonal
Granzyme H Antibody
Granzyme H Antibody
NBP1-86565
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
Granzyme H Overexpression Lys ...
Granzyme H Overexpression Lysate (...
H00002999-T01
Species: Hu
Applications: WB
Granzyme H Overexpression Lys ...
Granzyme H Overexpression Lysate (...
NBP2-05880
Applications: WB
Proteins
Granzyme H Recombinant Protei ...
Granzyme H Recombinant Protein Ant...
NBP1-86565PEP
Species: Hu
Applications: AC
Granzyme H Recombinant Protei ...
Granzyme H Recombinant Protein
NBP2-52043
Species: Hu
Applications: PAGE
Granzyme H Recombinant Protei ...
Granzyme H Recombinant Protein
NBP2-50560
Species: Hu
Applications: PAGE
RNAi
Granzyme H RNAi
Granzyme H RNAi
H00002999-R01
Species: Hu

Description

The granzyme family of proteins belong to the larger peptidase S1 family. Granzyme A and granzyme B are serine proteases that facilitate apoptotic signaling in cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. Within the granules of activated CTLs, granzyme A and granzyme B are processed and converted to their active forms by the lysosomal cysteine protease cathepsin C. Once cleaved, these active proteases target distinct substrates for proteolysis and, thereby, mediate apoptosis through two different pathways. Granzyme H, also designated cytotoxic T-lymphocyte proteinase, cathepsin G-like 2 (CTSGL2) or cytotoxic serine protease C (CSP-C), contains one peptidase S1 domain. Granzyme H localizes to cytoplasmic granules of cytolytic T-lymphocytes and is important for target cell lysis in cell-mediated immune responses.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2999
Alternate Names
  • EC 3.4.21.79
  • Cytotoxic serine protease C
  • EC 3.4.21
  • Cathepsin G-like 2
  • EC 3.4.21.-
  • CTLA1
  • CGL2
  • CGL-2
  • CTSGL2granzyme H
  • CSP-Ccytotoxin serine protease-C
  • CCP-Xcytotoxic T-lymphocyte-associated serine esterase 1
  • Cytotoxic T-lymphocyte proteinase
  • granzyme H (cathepsin G-like 2, protein h-CCPX)

Research Areas for Granzyme H

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for Granzyme H

Learn more about PTMs related to Granzyme H.

Cleavage

Bioinformatics Tool for Granzyme H

Discover related pathways, diseases and genes to Granzyme H. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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