Species: Hu, Mu, Rt, Bv, Ca, Eq, Ha, Pm, Pm
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Hu, Rt, Pm, Pm, Eq, Ma-OpApplications:
WB, IHC, IHC-PHost:
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.
Research Areas for Glucagon R/GCGR
Find related products by research area and learn more about each of the different research areas below.GPCRSignal Transduction
Bioinformatics Tool for Glucagon R/GCGR
Discover related pathways, diseases and genes to Glucagon R/GCGR. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.