Glucagon R/GCGR Products

Description

Glucagon, a pancreatic hormone, functions as an antagonist to insulin, stimulating the conversion of glycogen to glucose and increasing blood sugar levels. GLP-1 functions as a transmitter in the central nervous system, inhibiting feeding and drinking behavior. Both glucagon and GLP-1 function through their specific binding to the glucagon receptor or GLP-1R, respectively. The glucagon receptor shows expression in liver, kidney and adipose tissue. The 56 GLP-1R expression primarily localizes to areas of the hypothalamus involved in feeding behavior. Both receptors and their ligands serve as potential targets for the therapeutic treatment of diabetes.

Bioinformatics

Entrez	14527 Mouse 24953 Rat 2642 Human
Uniprot	NM_000160 Human NP_000151.1 Human P47871 Human
Product By Gene ID	2642
Alternate Names	FLJ97182 GGR GL-R glucagon receptor MGC138246

Research Areas for Glucagon R/GCGR

Find related products by research area and learn more about each of the different research areas below.

GPCR
Signal Transduction