GLP1 Products

Description

Glucagon-like peptide-1 (GLP-1) is an incretin hormone secreted from enteroendocrine L cells in response to ingested nutrients. The closely related peptides glucagon-like peptide (GLP-1) and glucagon have opposing effects on blood glucose. GLP-1 induces glucose-dependent insulin secretion in the pancreas, while glucagon stimulates gluconeogenesis and glycogenolysis in the liver. Glucagon is processed from a large precursor, proglucagon, in a tissue-specific manner in pancreatic alpha-cells. The identification of a hybrid peptide acting as both a GLP-1 agonist and a glucagon antagonist would provide a novel approach for the treatment of type 2 diabetes.

Bioinformatics

Entrez	2641 Human 2740 Human
Uniprot	P01275 Human P43220 Human
Product By Gene ID	2641
Alternate Names	glicentin-related polypeptide GLP1 glucagon-like peptide 1 GRPP

Diseases related to GLP1

Discover more about diseases related to GLP1.

Diabetes Mellitus, Non-insulin-dependent
Diabetes Mellitus
Metabolic Diseases
Obesity
Impaired Glucose Tolerance
Hyperplasia
Glucagon Deficiency
Nervous System Disorder
Diphtheria
Haploinsufficiency
Diabetes Mellitus, Experimental
Peripheral Neuropathy
Nervousness
Leukemia
Hyperglycemia

Pathways for GLP1

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Secretion
Insulin Secretion
Reverse Transcription
Cell Proliferation
Gluconeogenesis
Glucagon Secretion
Response To Camp
Glucose Homeostasis
Dna Replication
Hormone Secretion
Tricarboxylic Acid Cycle
Peptide Hormone Secretion
Translation
Cell Differentiation
Regulation Of Glucagon Secretion

Research Areas for GLP1

Find related products by research area and learn more about each of the different research areas below.

Cancer
GPCR
Signal Transduction

PTMs for GLP1

Learn more about PTMs related to GLP1.

Phosphorylation
Cleavage

Bioinformatics Tool for GLP1

Discover related pathways, diseases and genes to GLP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.