GAD2/GAD65 Products

Antibodies
GAD2/GAD65 Antibody
GAD2/GAD65 Antibody
NBP1-33284
Species: Hu, Mu, Rt, Bovine, Canine, Porcine, Monkey
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GAD2/GAD65 Antibody
GAD2/GAD65 Antibody
NB110-41528
Species: Hu, Mu, Rt, Po, Ha, Mk
Applications: WB, IHC, IHC-P, In vitro, MiAr
Host: Rabbit Polyclonal
GAD2/GAD65 Antibody (2736)
GAD2/GAD65 Antibody (2736)
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Antibody Pairs
GAD2/GAD65 Antibody Pair
GAD2/GAD65 Antibody Pair
H00002572-PW1
Species: Hu
Applications: WB, IP
Lysates
GAD2/GAD65 Overexpression Lys ...
GAD2/GAD65 Overexpression Lysate (...
NBP2-11101
Applications: WB
GAD2/GAD65 Overexpression Lys ...
GAD2/GAD65 Overexpression Lysate (...
NBP2-10700
Applications: WB
GAD2/GAD65 Overexpression Lys ...
GAD2/GAD65 Overexpression Lysate (...
H00002572-T01
Species: Hu
Applications: WB
Proteins
GAD2/GAD65 Recombinant Protei ...
GAD2/GAD65 Recombinant Protein
H00002572-P02
Species: Hu
Applications: WB, ELISA, PA
GAD2/GAD65 Recombinant Protei ...
GAD2/GAD65 Recombinant Protein Ant...
NBP1-89801PEP
Species: Hu
Applications: AC
GAD2/GAD65 Recombinant Protei ...
GAD2/GAD65 Recombinant Protein
H00002572-P03
Species: Hu
Applications: ELISA, PA

Description

Antibodies to glutamic acid decarboxylase-65 (GAD65) are present in autoimmune disorders such as insulin-dependent (type 1) diabetes mellitus (IDDM), stiff man syndrome and polyendocrine autoimmune disease. Auto-antibodies to GAD65 are present in 60-70% of individuals with newly diagnosed IDDM and thus are important markers for disease activity. These auto-antibodies usually recognize conformation-dependent regions on GAD65 and rarely bind to the second isoform, GAD67. Auto-antibodies to GAD67 are found in only 15% of recent-onset IDDM patients and most of this binding can be blocked with GAD65, suggesting shared epitopes between the two isoforms of GAD.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2572
Alternate Names
  • EC 4.1.1
  • EC 4.1.1.15
  • Glutamate decarboxylase-2 (pancreas)
  • GAD-65
  • glutamate decarboxylase 2
  • MGC161607,65 kDa glutamic acid decarboxylase
  • Glutamate decarboxylase 65 kDa isoform
  • GAD65MGC161605
  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kD)
  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)

Research Areas for GAD2/GAD65

Find related products by research area and learn more about each of the different research areas below.

Diabetes Research
Immune System Diseases
Immunology
Lipid and Metabolism
Neuronal Cell Markers
Neuroscience

PTMs for GAD2/GAD65

Learn more about PTMs related to GAD2/GAD65.

Methylation
Demethylation
Acetylation

Bioinformatics Tool for GAD2/GAD65

Discover related pathways, diseases and genes to GAD2/GAD65. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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