GABPA Products

Description

GABPA encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.

Bioinformatics

Entrez	2551 Human
Uniprot	Q06546 Human AAH35031 Human AAH35031.1 Human NM_002040 Human NP_002031 Human
Product By Gene ID	2551
Alternate Names	human nuclear respiratory factor-2 subunit alpha, 10 nuclear respiratory factor 2 alpha subunit NRF2A GA-binding protein alpha chain NRF2 GA-binding protein transcription factor, alpha subunit (60kD) NFT2 GABP subunit alpha E4TF1-60 E4TF1ATranscription factor E4TF1-60 Nuclear respiratory factor 2 subunit alpha GA binding protein transcription factor, alpha subunit 60kDa

Diseases related to GABPA

Discover more about diseases related to GABPA.

Malignant Neoplasms
Down Syndrome
Neoplasms
Systemic Infection
Immunologic Deficiency Syndromes
Liver Carcinoma
Retinoblastoma
Malignant Neoplasm Of Breast
Mitochondrial Damage
Mammary Neoplasms
Dystrophy
Inflammation
Trisomy
Hiv Infections
Muscular Dystrophy
Dementia
Myasthenic Syndromes, Congenital
Dysplasia
Paroxysmal Nocturnal Dyspnea

Pathways for GABPA

View related products by pathway and learn more about each of the pathways below.

Localization
Cell Development
Dna Methylation
Methylation
Oxidative Phosphorylation
Translation
Cell Proliferation
Rna Interference
Hyperphosphorylation
Cell Activation
Cell Migration
Tricarboxylic Acid Cycle
T Cell Activation
Fertilization
Aging
Immune Response
Dna Demethylation
Regulation Of Gene Expression
Histone Modification
Limb Development

PTMs for GABPA

Learn more about PTMs related to GABPA.

Phosphorylation
Methylation
Acetylation
Oxidation
Demethylation
Reduction
Cleavage
Deacetylation

Bioinformatics Tool for GABPA

Discover related pathways, diseases and genes to GABPA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 

Related GABPA Blog Posts

Check out the latest blog posts on GABPA.

The effects of ethanol consumption on glutamate production and xCT xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox...    Read more.

Read more GABPA related blogs.