GABPA Products

Description

GABPA encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype.

Bioinformatics

Entrez	2551 Human
Uniprot	AAH35031 Human AAH35031.1 Human NM_002040 Human NP_002031 Human Q06546 Human
Product By Gene ID	2551
Alternate Names	E4TF1-60 E4TF1ATranscription factor E4TF1-60 GA binding protein transcription factor, alpha subunit 60kDa GA-binding protein alpha chain GA-binding protein transcription factor, alpha subunit (60kD) GABP subunit alpha human nuclear respiratory factor-2 subunit alpha, 10 NFT2 NRF2 NRF2A nuclear respiratory factor 2 alpha subunit Nuclear respiratory factor 2 subunit alpha

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The effects of ethanol consumption on glutamate production and xCT xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox...    Read more.

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