GABARAPL1 Products

Antibodies
GABARAPL1 Antibody
GABARAPL1 Antibody
NBP1-55202
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
GABARAPL1 Antibody
GABARAPL1 Antibody
NBP1-55203
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
GABARAPL1 Antibody
GABARAPL1 Antibody
NBP2-14032
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
GABARAPL1 Recombinant Protein ...
GABARAPL1 Recombinant Protein Antigen
NBP2-14032PEP
Species: Hu
Applications: AC
GABARAPL1 Recombinant Protein ...
GABARAPL1 Recombinant Protein
NBP1-50916
Applications: PAGE

Description

Ubiquitin-like proteins fall into two classes: the first class, ubiquitin-like modifiers (UBLs)function as modifiers in a manner analogous to that of ubiquitin. Examples of UBLs are SUMO, Rub1 (also called Nedd8), Apg8 and Apg12. Proteins of the second class include parkin, RAD23 and DSK2, are designated ubiquitin-domain proteins (UDPs). These proteins contain domains that are related to ubiquitin but are otherwise unrelated to each other. In contrast to UBLs, UDPs are not conjugated to other proteins. Apg8 is required for autophagy (intracellular bulk protein degradation) in yeast. Starved yeast cells take up their own cytoplasm into vacuoles through autophagic bodies. Autophagic bodies form a double-membraned structure called the autophagosome,which subsequently fuses with the vacuole/lysosome. This process similar in mammals. Two sets of genes, APG and AUT, have been identified with this process, and are responsible for two ubiquitin-like systems Apg12 and Apg8, respectively. Apg12 is synthesized in its mature form and seems to have one target, Apg5. Almost all Apg12 molecules are conjugated with Apg5. Aut2/Apg4 processes the Apg8/Aut7 system at its carboxy-terminal region. Apg8 exists in two forms, one is membrane bound through a phospholipid. Lipidation/ activation of Apg8 is mediated by Apg7 and transferred to Apg3 and finally forms a conjugate with phosphatidyl-ethanolamine (PE). Apg4 cleaves Apg8

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 23710
Alternate Names
  • Glandular epithelial cell protein 1
  • gamma-aminobutyric acid receptor-associated protein-like 1
  • Early estrogen-regulated protein
  • ATG8
  • ATG8L
  • APG8-LIKE
  • ATG8B
  • gec1
  • APG8L
  • GEC1GABA(A) receptor-associated protein-like 1
  • GEC-1
  • GABA(A) receptor-associated protein like 1

Research Areas for GABARAPL1

Find related products by research area and learn more about each of the different research areas below.

Autophagy

PTMs for GABARAPL1

Learn more about PTMs related to GABARAPL1.

Phosphorylation
Cleavage
Dephosphorylation

Bioinformatics Tool for GABARAPL1

Discover related pathways, diseases and genes to GABARAPL1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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