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The GABRB3 gene encodes a member of the ligand-gated ionic channel family. The encoded protein, GABA A Receptor beta 3, is one of at least 13 distinct subunits of a multisubunit chloride channel that serves as the receptor for gamma-aminobutyric acid, the major inhibitory transmitter of the nervous system. GABRB3 is located on the long arm of chromosome 15 in a cluster with two genes encoding related subunits of the family. Mutations in the GABA A Receptor beta 3 gene may be associated with the pathogenesis of Angelman syndrome, Prader-Willi syndrome, and autism.
![Western Blot GABA-A R beta 3 [p Ser409, p Ser408] Antibody - Azide Free](http://images.novusbio.com/fullsize/GABA-A-R-beta-3-[p-Ser409--p-Ser408]-Antibody-Western-Blot-NBP2-29508-img0002.jpg)
