Fucosyltransferase 8/FUT8 Products

Description

FUT8 belongs to the family of fucosyltransferases. The product of this gene catalyzes the transfer of fucose from GDP-fucose to N-linked type complex glycopeptides. This enzyme is distinct from other fucosyltransferases which catalyze alpha1-2, alpha1-3, and alpha1-4 fucose addition. The expression of this gene may contribute to the malignancy of cancer cells and to their invasive and metastatic capabilities. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq]

Bioinformatics

Entrez	2530 Human
Uniprot	NP_004471 Human NP_835368 Human NP_835369 Human
Product By Gene ID	2530
Alternate Names	alpha-(1,6)-fucosyltransferase alpha1-6FucT EC 2.4.1.68 fucosyltransferase 8 (alpha (1,6) fucosyltransferase) Fucosyltransferase 8 GDP-fucose--glycoprotein fucosyltransferase GDP-L-Fuc:N-acetyl-beta-D-glucosaminide alpha1,6-fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase MGC26465