Frizzled-2 Products

Antibodies
Frizzled-2 Antibody (202102)
Frizzled-2 Antibody (202102)
MAB1307
Species: Hu, Mu
Applications: WB, IP
Host: Rat Monoclonal
Frizzled-2 Antibody
Frizzled-2 Antibody
NBP2-33842
Species: Hu, Mouse, Rat
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Frizzled-2 Antibody
Frizzled-2 Antibody
AF1307
Species: Mu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Proteins
Frizzled-2 Partial Recombinan ...
Frizzled-2 Partial Recombinant Pro...
H00002535-Q01
Species: Hu
Applications: WB, ELISA, PA
Frizzled-2 Recombinant Protei ...
Frizzled-2 Recombinant Protein Ant...
NBP2-33842PEP
Species: Hu
Applications: AC
RNAi
Frizzled-2 RNAi
Frizzled-2 RNAi
H00002535-R02
Species: Hu

Description

Frizzled 2 is a receptor for Wnt proteins. Most of the frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of dishevelled proteins, inhibition of GSK3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK3 kinase. Both pathways seem to involve interactions with G-proteins.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Mouse
Product By Gene ID 2535
Alternate Names
  • frizzled-2
  • FzE2
  • Fz2
  • Fz-2
  • frizzled (Drosophila) homolog 2
  • fzE2
  • hFz2
  • fz-2
  • frizzled homolog 2 (Drosophila)

Research Areas for Frizzled-2

Find related products by research area and learn more about each of the different research areas below.

Cancer
GPCR
Growth and Development
Neuronal Cell Markers
Wnt Signaling Pathway

PTMs for Frizzled-2

Learn more about PTMs related to Frizzled-2.

Phosphorylation
Glycosylation
Methylation
Ubiquitination

Bioinformatics Tool for Frizzled-2

Discover related pathways, diseases and genes to Frizzled-2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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