Folliculin Products

Description

Belonging to the folliculin family, this gene is involved in the regulation of protein phosphorylation and protein binding. Located on chromosome 17 within the Smith-Magenis region, folliculin is a possible tumor suppressor gene associated with hereditary renal carcinoma. Mutations in this gene are associated with Birt-Hogg Dube syndrome. Folliculin may play a role in the pathogenesis of kidney cancer. Additionally, this gene may be involved in colorectal tomorigenesis and is also known to be involved in energy and nutrient sensing through the AMPK and mTOR signaling pathways. Common diseases associated with this gene include renal-cell carcinoma, colorectal cancer, renal cancer, Birt-Hogg-Dube syndrome and primary spontaneous pneumothorax.

Bioinformatics

Entrez	201163 Human 216805 Mouse
Uniprot	NM_144606 Human AAH15687 Human NP_659434 Human NP_653207 Human NP_653207.1 Human Q8NFG4 Human Q8QZS3 Mouse
Product By Gene ID	201163
Alternate Names	BHD skin lesion fibrofolliculoma protein Birt-Hogg-Dube syndrome protein FLJ99377 MGC23445 FLJ45004 MGC17998 BHDFLCL DKFZp547A118 folliculin

Diseases related to Folliculin

Discover more about diseases related to Folliculin.

Kidney Neoplasm
Neoplasms
Multiple Fibrofolliculomas
Malignant Neoplasms
Renal Cell Carcinoma
Carcinoma
Malignant Neoplasm Of Kidney
Spontaneous Pneumothorax
Skin Diseases, Genetic
Skin Neoplasms
Lung Diseases
Neoplastic Syndromes, Hereditary
Von Hippel-lindau Syndrome
Oncocytic Neoplasm
Germline Mutation Abnormality
Hamartoma
Dermatologic Disorders
Chromophobe Renal Cell Carcinoma
Tuberous Sclerosis

Pathways for Folliculin

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Pathogenesis
Oxidative Phosphorylation
Localization
Methylation
Tricarboxylic Acid Cycle
Cell Death
Cell Adhesion
Cell Migration
Cell Proliferation
Induction Of Apoptosis
Aging
Stem Cell Maintenance
Amino Acid Homeostasis
Cytokinesis
Mismatch Repair
Dna Replication
Cell Cycle
Interphase
Angiogenesis
Glycolysis

Research Areas for Folliculin

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Cancer
Cell Cycle and Replication

PTMs for Folliculin

Learn more about PTMs related to Folliculin.

Phosphorylation
Methylation
Carboxylation

Bioinformatics Tool for Folliculin

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