Folliculin Products

Description

Belonging to the folliculin family, this gene is involved in the regulation of protein phosphorylation and protein binding. Located on chromosome 17 within the Smith-Magenis region, folliculin is a possible tumor suppressor gene associated with hereditary renal carcinoma. Mutations in this gene are associated with Birt-Hogg Dube syndrome. Folliculin may play a role in the pathogenesis of kidney cancer. Additionally, this gene may be involved in colorectal tomorigenesis and is also known to be involved in energy and nutrient sensing through the AMPK and mTOR signaling pathways. Common diseases associated with this gene include renal-cell carcinoma, colorectal cancer, renal cancer, Birt-Hogg-Dube syndrome and primary spontaneous pneumothorax.

Bioinformatics

Entrez	201163 Human 216805 Mouse
Uniprot	AAH15687 Human NM_144606 Human NP_653207 Human NP_653207.1 Human NP_659434 Human Q8NFG4 Human Q8QZS3 Mouse
Product By Gene ID	201163
Alternate Names	BHD skin lesion fibrofolliculoma protein BHDFLCL Birt-Hogg-Dube syndrome protein DKFZp547A118 FLJ45004 FLJ99377 folliculin MGC17998 MGC23445

Research Areas for Folliculin

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cell Cycle and Replication