Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
Host: Goat Polyclonal
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ELISA, PA
Species: Hu
Applications: AC
Description
F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. A large family of mammalian F-box proteins has recently been identified and classified into three groups based on the presence of either the WD-40 repeats, the leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. The FBXW2 gene product, the second identified member of the F-box gene family, contains multiple WD-40 repeats.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
|
| Product By Gene ID |
26190 |
| Alternate Names |
- F-box and WD-40 domain-containing protein 2
- Protein MD6
- F-box and WD-40 domain protein 2
- FWD2
- Md6
- F-box/WD repeat-containing protein 2
- FBW2Fwd2
- MGC117371
- F-box and WD repeat domain containing 2
|
Bioinformatics Tool for FBXW2
Discover related pathways, diseases and genes to FBXW2. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
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